Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GCK | P35557 | 2/20 | 0.38 |
| ▸ | F10 | P00742 | 8/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25796522 | 0.72 | GRM5 (0.45) | ALOX15KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL3007282 | 0.72 | GRM5 (0.45) | ALOX15KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL25796518 | 0.72 | NLRP3 (0.53) | — | |
| SCHEMBL25245222 | 0.71 | NLRP3 (0.53) | — | |
| SCHEMBL31054273 | 0.71 | GRM5 (0.44) | ALOX15KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL18334316 | 0.70 | F10 (0.51) | ALOX15KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL1251008 | 0.65 | F10 (0.50) | KDM4EALDH1A1MAPTF10GRM5 | |
| SCHEMBL10279507 | 0.65 | F10 (0.50) | ALOX15KDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL13372703 | 0.65 | GRM5 (0.46) | ALOX15KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL7898649 | 0.65 | F10 (0.53) | NPC1RAB9AF10GRM5F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116812-A1 | SULFONYLUREA COMPOUND | 瑞石生物医药有限公司 | 2023-06-29 | — | — | WO | disclosed |