Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | PPARD | Q03181 | 7/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | FABP4 | P15090 | 2/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16713413 | 1.00 | CA14 (0.53) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL6510544 | 0.94 | HDAC1 (0.49) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL31216313 | 0.94 | GPR84 (0.53) | CA14TSHRLMNAALDH1A1GPR84 | |
| SCHEMBL20262970 | 0.93 | CA14 (0.51) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL12901425 | 0.91 | CA14 (0.58) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL20556291 | 0.90 | GPR84 (0.48) | CA14TSHRALDH1A1GPR84PPARG | |
| SCHEMBL31504950 | 0.90 | CA14 (0.47) | CA14HDAC1HDAC2HDAC6TSHR | |
| SCHEMBL25628395 | 0.87 | CA14 (0.59) | CA14HDAC1HDAC2HDAC6TDP1 | |
| SCHEMBL16492823 | 0.87 | CA14 (0.51) | CA14TSHRALDH1A1GPR84PPARG | |
| SCHEMBL18675283 | 0.87 | CA14 (0.51) | CA14TSHRALDH1A1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295081-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | ARCTURUS THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| WO-2023086514-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | ARCTURUS THERAPEUTICS, INC. (US) | 2023-05-19 | — | — | WO | disclosed |
| US-20110269943-A1 | RADIOLABELED ANNEXINS | UNIVERSITY OF WASHINGTON (US) | 2011-11-03 | — | — | US | disclosed |
| US-7744853-B2 | Radiolabeled annexins | PONIARD PHARMACEUTICALS, INC. (US) | 2010-06-29 | — | — | US | disclosed |
| US-7115248-B2 | Radiolabeled annexins | NEORX CORPORATION (US) | 2006-10-03 | — | — | US | disclosed |
| US-20060029545-A1 | Radiolabeled annexins | NEORX CORPORATION, REGENTS OF THE UNIVERSITY OF MICHIGAN | 2006-02-09 | — | — | US | disclosed |
| US-6908903-B1 | Cluster clearing agents | ALETHEON PHARMACEUTICALS, INC. (US) | 2005-06-21 | — | — | US | disclosed |
| US-20050036948-A1 | Radiolabeled annexins | NEORX CORPORATION (US) | 2005-02-17 | — | — | US | disclosed |
| EP-1426062-A2 | Radiolabeled annexins | NEORX CORPORATION (US) | 2004-06-09 | — | — | EP | disclosed |
| EP-0918547-B1 | RADIOLABELED ANNEXINS | NEORX CORP (US) | 2004-03-10 | — | — | EP | disclosed |
| US-20030220233-A1 | Radiolabeled annexins | NEORX CORPORATION | 2003-11-27 | — | — | US | disclosed |
| US-20020137672-A1 | Radiolabeled annexins | KASINA SUDHAKAR (US) | 2002-09-26 | — | — | US | disclosed |
| US-6172045-B1 | COMPLEX CONTAINING 1-DESOXY-1-THIO-N-ACETYLGALACTOSAMINE | NEORX CORPORATION | 2001-01-09 | — | — | US | disclosed |
| US-6171577-B1 | ACCESSIBLE SULFHYDRYL GROUP; AND HEXOSE MOIETY RECOGNIZED BY A MAMMALIAN LIVER RECEPTOR, WHEREIN THE HEXOSE MOIETY IS CONJUGATED TO THE ANNEXIN. | NEORX CORPORATION | 2001-01-09 | — | — | US | disclosed |
| US-5968477-A | IMAGING AGENTS WITH SULFHYDRYL GROUPS AND HEXOSE GROUPS | NEORX CORPORATION (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0918547-A2 | RADIOLABELED ANNEXINS | NEORX CORPORATION (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004294-A2 | RADIOLABELED ANNEXINS | NEORX CORPORATION (US) | 1998-02-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295081-A1 | IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY | NSUN3, POLRMT, NPC1L1 | CA14 2668/4885HDAC1 703/4885HDAC2 865/4885 |
| US-20060029545-A1 | Radiolabeled annexins | ANXA11, ANXA1, ANXA3 | CA14 740/4885HDAC1 4383/4885HDAC2 4832/4885 |
| US-20050036948-A1 | Radiolabeled annexins | ANXA11, ANXA1, ANXA3 | CA14 740/4885HDAC1 4383/4885HDAC2 4832/4885 |
| US-20110269943-A1 | RADIOLABELED ANNEXINS | ANXA11, ANXA1, ANXA3 | CA14 740/4885HDAC1 4383/4885HDAC2 4832/4885 |
| US-20020137672-A1 | Radiolabeled annexins | ANXA11, ANXA1, ANXA3 | CA14 740/4885HDAC1 4383/4885HDAC2 4832/4885 |
| US-20030220233-A1 | Radiolabeled annexins | ANXA11, ANXA1, ANXA3 | CA14 740/4885HDAC1 4383/4885HDAC2 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.