Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 8/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25797127 | 0.88 | GPR119 (0.44) | GPR119MAPTMEN1KMT2AHDAC1 | |
| SCHEMBL18186327 | 0.85 | HSD11B1 (0.43) | GPR119MAPTMEN1KMT2AHDAC1 | |
| SCHEMBL18186328 | 0.85 | HSD11B1 (0.43) | GPR119MAPTMEN1KMT2AHDAC1 | |
| SCHEMBL25797157 | 0.83 | HSD11B1 (0.41) | GPR119CYP19A1MAPTHDAC1PARP1 | |
| SCHEMBL25797111 | 0.83 | HSD11B1 (0.41) | GPR119MAPTHDAC1PARP1HSD11B1 | |
| SCHEMBL25797118 | 0.82 | HSD11B1 (0.41) | GPR119MAPTHDAC1PARP1HSD11B1 | |
| SCHEMBL18186222 | 0.81 | HSD11B1 (0.44) | GPR119MAPTHDAC1PARP1HSD11B1 | |
| SCHEMBL18186221 | 0.81 | HSD11B1 (0.44) | GPR119MAPTHDAC1PARP1HSD11B1 | |
| SCHEMBL18186329 | 0.81 | HSD11B1 (0.44) | GPR119MAPTHDAC1PARP1HSD11B1 | |
| SCHEMBL18186374 | 0.81 | GPR119 (0.45) | GPR119MAPTHDAC1PARP1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203042-A1 | COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS | NANJING RUIJIE PHARMA CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203042-A1 | COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS | SYK, BTK, LCK | GPR119 792/4885CYP19A1 2244/4885CYP11B1 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.