Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 16/20 | 0.87 |
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.87 |
| ▸ | TNF | P01375 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22654829 | 0.93 | IL1B (1.00) | IL1BNLRP3TNF | |
| SCHEMBL25797799 | 0.93 | IL1B (0.82) | IL1BNLRP3TNF | |
| SCHEMBL22654851 | 0.93 | IL1B (1.00) | IL1BNLRP3TNF | |
| SCHEMBL22654826 | 0.93 | IL1B (1.00) | IL1BNLRP3TNF | |
| SCHEMBL24575326 | 0.92 | IL1B (0.81) | IL1BNLRP3TNF | |
| SCHEMBL25798980 | 0.92 | IL1B (0.84) | IL1BNLRP3 | |
| SCHEMBL29027415 | 0.91 | IL1B (0.79) | IL1BNLRP3TNF | |
| SCHEMBL29696972 | 0.91 | IL1B (0.79) | IL1BNLRP3TNF | |
| SCHEMBL25798820 | 0.91 | IL1B (0.79) | IL1BNLRP3TNF | |
| SCHEMBL25797808 | 0.90 | IL1B (0.78) | IL1BNLRP3TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129987-A1 | PYRIDAZINE DERIVATIVES AS MODULATORS OF NLRP3 INFLAMMASOME AND RELATED METHODS | Neumora Therapeutics, Inc. (US) | 2023-07-06 | — | — | WO | disclosed |