Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL1B | P01584 | 16/20 | 0.79 |
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.79 |
| ▸ | TNF | P01375 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25798820 | 1.00 | IL1B (0.79) | IL1BNLRP3TNF | |
| SCHEMBL29027415 | 1.00 | IL1B (0.79) | IL1BNLRP3TNF | |
| SCHEMBL25797809 | 0.91 | IL1B (0.87) | IL1BNLRP3TNF | |
| SCHEMBL25797799 | 0.89 | IL1B (0.82) | IL1BNLRP3TNF | |
| SCHEMBL22654826 | 0.89 | IL1B (1.00) | IL1BNLRP3TNF | |
| SCHEMBL22654829 | 0.89 | IL1B (1.00) | IL1BNLRP3TNF | |
| SCHEMBL22654851 | 0.89 | IL1B (1.00) | IL1BNLRP3TNF | |
| SCHEMBL25799056 | 0.89 | NLRP3 (0.69) | IL1BNLRP3 | |
| SCHEMBL24575326 | 0.88 | IL1B (0.81) | IL1BNLRP3TNF | |
| SCHEMBL25798829 | 0.88 | IL1B (0.75) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240391895-A1 | PYRIDAZINE-CONTAINING COMPOUND AND MEDICINAL USE THEREOF | QINGDAO BORSON TAI TECHNOLOGY CO., LTD. (CN) | 2024-11-28 | — | — | US | disclosed |
| CN-116390914-A | Pyridazine-containing compound and medical application thereof | 上海拓界生物医药科技有限公司 | 2023-07-04 | — | — | CN | disclosed |
| WO-2022135567-A1 | PYRIDAZINE-CONTAINING COMPOUND AND MEDICINAL USE THEREOF | 上海拓界生物医药科技有限公司 | 2022-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240391895-A1 | PYRIDAZINE-CONTAINING COMPOUND AND MEDICINAL USE THEREOF | NLRP3, NLRP1, NOD1 | IL1B 6/4885NLRP3 1/4885TNF 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.