Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25798311 | 0.92 | IL1B (0.64) | IL1BNLRP3 | |
| SCHEMBL25797972 | 0.89 | IL1B (0.61) | IL1BNLRP3 | |
| SCHEMBL25798116 | 0.89 | NLRP3 (0.66) | IL1BNLRP3 | |
| SCHEMBL25798114 | 0.87 | IL1B (0.58) | IL1BNLRP3 | |
| SCHEMBL25798128 | 0.87 | NLRP3 (0.66) | IL1BNLRP3 | |
| SCHEMBL25798593 | 0.86 | NLRP3 (0.63) | IL1BNLRP3 | |
| SCHEMBL25298002 | 0.86 | IL1B (0.75) | IL1BNLRP3 | |
| SCHEMBL30519498 | 0.86 | IL1B (0.75) | IL1BNLRP3 | |
| SCHEMBL25298003 | 0.86 | IL1B (0.75) | IL1BNLRP3 | |
| SCHEMBL25798438 | 0.86 | IL1B (0.75) | IL1BNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129987-A1 | PYRIDAZINE DERIVATIVES AS MODULATORS OF NLRP3 INFLAMMASOME AND RELATED METHODS | Neumora Therapeutics, Inc. (US) | 2023-07-06 | — | — | WO | disclosed |