SCHEMBL25798312

SCHEMBL25798312

CCNC(Cc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 2/20 0.65
ITGB7 P26010 2/20 0.65
MAPT P10636 5/20 0.54
TDP1 Q9NUW8 4/20 0.54
POLB P06746 4/20 0.54
CTSS P25774 2/20 0.51
CTSL P07711 1/20 0.51
CTSB P07858 1/20 0.51
CTSK P43235 1/20 0.51
MMP1 P03956 1/20 0.50
MMP3 P08254 1/20 0.50
MMP9 P14780 1/20 0.50
ACE P12821 1/20 0.49
ATM Q13315 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2C8 P10632 1/20 0.48
CYP2C9 P11712 1/20 0.48
NPR3 P17342 1/20 0.48
CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10957814 0.89 ITGA4 (0.54) ITGA4ITGB7MAPTTDP1POLB
SCHEMBL14957280 0.88 ITGA4 (0.65) ITGA4ITGB7MAPTTDP1POLB
SCHEMBL14139327 0.88 ITGA4 (0.52) ITGA4ITGB7MAPTTDP1POLB
SCHEMBL13611703 0.88 ITGA4 (0.52) ITGA4ITGB7MAPTTDP1POLB
SCHEMBL31622755 0.87 ITGA4 (0.51) ITGA4ITGB7MAPTTDP1POLB
SCHEMBL10956602 0.86 ITGA4 (0.62) ITGA4ITGB7MAPTTDP1POLB
SCHEMBL6428127 0.86 ITGA4 (0.62) ITGA4ITGB7MAPTTDP1POLB
SCHEMBL7428724 0.85 ITGA4 (0.59) ITGA4ITGB7MAPTTDP1POLB
SCHEMBL7428720 0.85 ITGA4 (0.59) ITGA4ITGB7MAPTTDP1POLB
SCHEMBL14732865 0.85 ITGA4 (0.76) ITGA4ITGB7MAPTTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023127869-A1 METHOD FOR PRODUCING N-ALKYL AMINO ACID AND PEPTIDE INCLUDING N-ALKYL AMINO ACID 中外製薬株式会社 2023-07-06 WO disclosed