Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 2/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 2/20 | 0.30 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576049 | 0.91 | PTGDR2 (0.37) | GPR4RXRAGRIN1GRIN2B | |
| SCHEMBL2580081 | 0.90 | USP1 (0.32) | GPR4RXRAGRIN1GRIN2BUSP1 | |
| SCHEMBL2579246 | 0.88 | PTGDR2 (0.34) | GPR4 | |
| SCHEMBL2570644 | 0.86 | PTGDR2 (0.44) | — | |
| SCHEMBL2574521 | 0.85 | USP1 (0.32) | USP1 | |
| SCHEMBL2573616 | 0.84 | PTGDR2 (0.36) | USP1 | |
| SCHEMBL2579403 | 0.83 | — | — | |
| SCHEMBL2576048 | 0.81 | PTGDR2 (0.37) | GPR4RXRAGRIN1GRIN2BUSP1 | |
| SCHEMBL2579240 | 0.78 | PTGDR2 (0.34) | GPR4 | |
| SCHEMBL2575104 | 0.78 | PTGDR2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139881-B1 | QUINOLINES AND THEIR THERAPEUTIC USE | PULMAGEN THERAPEUTICS ASTHMA LTD (GB) | 2011-11-09 | — | — | EP | claimed |
| EP-2139881-A1 | QUINOLINES AND THEIR THERAPEUTIC USE | Argenta Oral Therapeutics Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008122784-A1 | QUINOLINES AND THEIR THERAPEUTIC USE | ARGENTA DISCOVERY LIMITED (GB) | 2008-10-16 | — | — | WO | disclosed |