Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 3/20 | 0.40 |
| ▸ | SMPD3 | Q9NY59 | 2/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25801350 | 0.81 | SMPD3 (0.41) | SMPD3POLBMAPTALDH1A1GAA | |
| SCHEMBL23048328 | 0.81 | SMPD3 (0.41) | SMPD3POLBMAPTALDH1A1GAA | |
| SCHEMBL20128584 | 0.68 | POLB (0.38) | HRH4POLBMAPTALDH1A1PDE10A | |
| SCHEMBL18053572 | 0.68 | POLB (0.43) | POLBALDH1A1GAAPDE10AKDM4E | |
| SCHEMBL2162691 | 0.68 | ALDH1A1 (0.40) | POLBALDH1A1GAAPDE10AKDM4E | |
| SCHEMBL12324150 | 0.68 | POLB (0.40) | POLBMAPTALDH1A1GAAPDE10A | |
| SCHEMBL23048330 | 0.66 | POLB (0.39) | POLBTLR8KDM4E | |
| SCHEMBL23964777 | 0.66 | POLB (0.39) | POLBTLR8KDM4E | |
| SCHEMBL12403839 | 0.66 | MAPT (0.42) | IKBKBKMT2ATLR8MAPTALDH1A1 | |
| SCHEMBL18867172 | 0.65 | MAPT (0.41) | IKBKBHRH4HRH3KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218782-A1 | IMAGING METHODS USING DEUTERATED COMPOUNDS | GENENTECH, INC. (US) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218782-A1 | IMAGING METHODS USING DEUTERATED COMPOUNDS | SLC10A1, SLC9B2, RXFP1 | IKBKB 4078/4885SMPD3 967/4885HRH4 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.