SCHEMBL25801462

SCHEMBL25801462

CN(OC(=O)c1ccccc1)[C@H](C(=O)O)C1CCCC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
CYP2D6 P10635 1/20 0.45
SCN1A P35498 1/20 0.45
SCN2A Q99250 1/20 0.45
SCN3A Q9NY46 1/20 0.45
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
ATM Q13315 1/20 0.42
CHRNA7 P36544 2/20 0.40
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18815435 0.73 TSHR (0.47) LMNACYP1A2CYP2D6KMT2ATSHR
SCHEMBL18849868 0.73 TSHR (0.47) LMNACYP1A2CYP2D6KMT2ATSHR
SCHEMBL27713497 0.73 TSHR (0.50) LMNACYP1A2CYP2D6KMT2ATSHR
SCHEMBL29114259 0.72 TSHR (0.46) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL6347810 0.71 LMNA (0.40) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL28803763 0.71 LMNA (0.65) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL27252418 0.71 TSHR (0.44) LMNACYP1A2CYP2D6KMT2ATSHR
SCHEMBL17138261 0.71 L3MBTL1 (0.51) KMT2AMEN1ATMTSHRL3MBTL1
SCHEMBL842289 0.69 LMNA (0.58) LMNACYP1A2CYP2D6SCN1ASCN2A
SCHEMBL7505914 0.69 MEN1 (0.46) LMNACYP1A2CYP2D6SCN1ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023127869-A1 METHOD FOR PRODUCING N-ALKYL AMINO ACID AND PEPTIDE INCLUDING N-ALKYL AMINO ACID 中外製薬株式会社 2023-07-06 WO disclosed