Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706452 | 0.82 | — | — | |
| SCHEMBL2705752 | 0.82 | — | — | |
| SCHEMBL28056778 | 0.82 | — | — | |
| SCHEMBL490278 | 0.74 | — | — | |
| SCHEMBL1546863 | 0.65 | APLNR (1.00) | APLNRKDM4EMAPTKMT2AATM | |
| SCHEMBL18254435 | 0.65 | APLNR (1.00) | APLNRKDM4EMAPTKMT2AATM | |
| SCHEMBL20635078 | 0.65 | APLNR (0.69) | APLNRKDM4EMAPTKMT2AATM | |
| SCHEMBL18254434 | 0.65 | APLNR (1.00) | APLNRKDM4EMAPTKMT2AATM | |
| Sulfamide SCHEMBL27856392 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL18246458 | 0.64 | APLNR (0.96) | APLNRKDM4EMAPTKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970282-A1 | TRICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | Incyte Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014143768-A1 | TRICYCLIC HETEROCYCLES AS BET PROTEIN INHIBITORS | INCYTE CORPORATION (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2011137447-A1 | ANTIVIRAL COMPOUNDS | PROSTETTA ANTIVIRAL INC. (US) | 2011-11-03 | — | — | WO | disclosed |