SCHEMBL25801790

SCHEMBL25801790

CCCCc1ccc(Cc2noc(CC(C(=O)OC(C)(C)C)P(C)(=O)OCC)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.32
GAA P10253 1/20 0.32
PLK1 P53350 1/20 0.32
APLNR P35414 2/20 0.31
PPARG P37231 1/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
SRC P12931 5/20 0.31
ZAP70 P43403 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25801813 0.97 SRC (0.33) MEN1KMT2ALMNASRC
SCHEMBL25801972 0.95 MEN1 (0.35) MEN1KMT2ALMNASRCZAP70
SCHEMBL25802066 0.93 PRSS1 (0.32) MEN1KMT2ALMNATP53GAA
SCHEMBL23578163 0.92 MEN1 (0.33) MEN1KMT2ALMNATP53GAA
SCHEMBL25801818 0.91 MEN1 (0.40) MEN1KMT2ALMNAAPLNRPPARG
SCHEMBL25801911 0.91 MAPT (0.37) MEN1KMT2ALMNAKDM4E
SCHEMBL25804866 0.89 SRC (0.34) MEN1KMT2ASRC
SCHEMBL25801774 0.89 KMT2A (0.36) MEN1KMT2ALMNATP53PPARG
SCHEMBL25801748 0.89 MAPT (0.41) MEN1KMT2ALMNASRCZAP70
SCHEMBL25801969 0.89 MEN1 (0.35) MEN1KMT2ALMNASRCZAP70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES CPA2, RO60, C5AR1 MEN1 4504/4885KMT2A 3125/4885LMNA 3388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.