SCHEMBL25801813

SCHEMBL25801813

CCCCCc1ccc(Cc2noc(CC(C(=O)OC(C)(C)C)P(C)(=O)OCC)n2)cc1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SRC P12931 7/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
S1PR1 P21453 5/20 0.33
LMNA P02545 1/20 0.33
S1PR3 Q99500 4/20 0.33
S1PR2 O95136 2/20 0.33
LPAR2 Q9HBW0 1/20 0.33
S1PR4 O95977 3/20 0.32
SPHK1 Q9NYA1 1/20 0.32
S1PR5 Q9H228 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25801790 0.97 MEN1 (0.34) SRCMEN1KMT2ALMNA
SCHEMBL25801972 0.94 MEN1 (0.35) SRCMEN1KMT2ALMNA
SCHEMBL25804866 0.92 SRC (0.34) SRCMEN1KMT2AS1PR1S1PR3
SCHEMBL25801911 0.90 MAPT (0.37) MEN1KMT2AS1PR1LMNAS1PR3
SCHEMBL25802066 0.90 PRSS1 (0.32) SRCMEN1KMT2AS1PR1LMNA
SCHEMBL23578163 0.89 MEN1 (0.33) SRCMEN1KMT2ALMNA
SCHEMBL25801969 0.88 MEN1 (0.35) SRCMEN1KMT2ALMNA
SCHEMBL25801748 0.88 MAPT (0.41) SRCMEN1KMT2ALMNA
SCHEMBL25801926 0.88 SRC (0.34) SRC
SCHEMBL25801915 0.88 SRC (0.34) SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES SITRYX THERAPEUTICS LIMITED (GB) 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219907-A1 CARBOXY DERIVATIVES WITH ANTIINFLAMATORY PROPERTIES CPA2, RO60, C5AR1 SRC 4647/4885MEN1 4504/4885KMT2A 3125/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.