Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | JAK2 | O60674 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.41 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12536251 | 0.94 | CHRNB2 (0.48) | CHRNB2CHRNA4JAK2CYP1A2CYP3A4 | |
| SCHEMBL12505408 | 0.88 | JAK2 (0.42) | CHRNB2CHRNA4JAK2JAK1TYK2 | |
| SCHEMBL14962150 | 0.86 | ACHE (0.44) | JAK2JAK1TYK2JAK3ACHE | |
| SCHEMBL2737310 | 0.86 | ACHE (0.47) | CHRNB2CHRNA4JAK2JAK1TYK2 | |
| SCHEMBL10141501 | 0.84 | ACHE (0.46) | CHRNB2CHRNA4JAK2JAK1TYK2 | |
| SCHEMBL10141528 | 0.82 | KDM5B (0.39) | CHRNB2CHRNA4JAK2ACHEKDM5B | |
| SCHEMBL24086679 | 0.82 | CHRNB2 (0.46) | CHRNB2CHRNA4JAK2CYP1A2CYP3A4 | |
| SCHEMBL24747359 | 0.78 | CHRNB2 (0.43) | CHRNB2CHRNA4JAK2CYP1A2CYP3A4 | |
| SCHEMBL17306121 | 0.78 | KHK (0.35) | CHRNB2CHRNA4JAK2CYP1A2CYP3A4 | |
| SCHEMBL22794284 | 0.77 | ACHE (0.40) | ACVRL1ACVR1ACHEKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023115150-A1 | BIFUNCTIONAL ARYLSULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2023-06-29 | — | — | WO | disclosed |