Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 6/20 | 0.49 |
| ▸ | SRC | P12931 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | BCR | P11274 | 2/20 | 0.44 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958932 | 1.00 | TMPRSS2 (0.53) | TMPRSS2ABL1SRCALDH1A1MAPT | |
| SCHEMBL29958978 | 0.93 | ABL1 (0.51) | TMPRSS2ABL1SRCBRAFKIT | |
| SCHEMBL25802478 | 0.93 | ABL1 (0.51) | TMPRSS2ABL1SRCBRAFKIT | |
| SCHEMBL29959139 | 0.85 | ABL1 (0.53) | ABL1SRCALDH1A1MAPTMEN1 | |
| SCHEMBL2776874 | 0.85 | ABL1 (0.53) | ABL1SRCALDH1A1MAPTMEN1 | |
| SCHEMBL23326866 | 0.84 | MKNK2 (0.58) | ABL1SRCMAPTKMT2ABRAF | |
| SCHEMBL2435253 | 0.84 | ABL1 (0.65) | ABL1SRCBRAFKITGAA | |
| SCHEMBL29999023 | 0.84 | MKNK2 (0.58) | ABL1SRCMAPTKMT2ABRAF | |
| Hydrochloric Acid SCHEMBL2435251 | 0.83 | ABL1 (0.64) | ABL1SRCBRAFKITGAA | |
| SCHEMBL29958955 | 0.83 | ABL1 (0.47) | ABL1SRCALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210853-A1 | TARGETED NEK7 INHIBITION FOR MODULATION OF THE NLRP3 INFLAMMASOME | Halia Therapeutics, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210853-A1 | TARGETED NEK7 INHIBITION FOR MODULATION OF THE NLRP3 INFLAMMASOME | NEK7, NLRP3, NOD1 | TMPRSS2 1015/4885ABL1 4556/4885SRC 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.