SCHEMBL2580308

SCHEMBL2580308

NCCCCC(NC(=O)CCCCC(S)CCS)C(=O)O.[Zn]

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 1/20 0.55
FOLH1 Q04609 2/20 0.50
NOD1 Q9Y239 5/20 0.46
GNPAT O15228 1/20 0.43
RNPEP Q9H4A4 1/20 0.41
NMT2 O60551 1/20 0.41
NMT1 P30419 1/20 0.41
FNTA P49354 3/20 0.40
FNTB P49356 3/20 0.40
PGGT1B P53609 1/20 0.40
CPB2 Q96IY4 2/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
SLC15A2 Q16348 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2581261 0.99 SLC6A5 (0.56) SLC6A5FOLH1NOD1GNPATRNPEP
SCHEMBL2520684 0.99 SLC6A5 (0.56) SLC6A5FOLH1NOD1GNPATRNPEP
SCHEMBL2577664 0.86 FOLH1 (0.44) SLC6A5FOLH1NOD1GNPATFNTA
SCHEMBL2577659 0.86 FOLH1 (0.44) SLC6A5FOLH1NOD1GNPATFNTA
SCHEMBL18807817 0.86 SLC6A5 (0.59) SLC6A5FOLH1NOD1GNPATNMT2
SCHEMBL16187739 0.86 SLC6A5 (0.59) SLC6A5FOLH1NOD1GNPATNMT2
SCHEMBL16187733 0.86 SLC6A5 (0.59) SLC6A5FOLH1NOD1GNPATNMT2
SCHEMBL16187737 0.86 SLC6A5 (0.59) SLC6A5FOLH1NOD1GNPATNMT2
SCHEMBL14854318 0.86 SLC6A5 (0.59) SLC6A5FOLH1NOD1GNPATNMT2
SCHEMBL16187738 0.86 SLC6A5 (0.59) SLC6A5FOLH1NOD1GNPATNMT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8048911-B2 Melanin eliminator preparation OGA Research, Inc. (JP) 2011-11-01 US disclosed
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION OGA RESEARCH, INC (JP) 2009-04-09 US disclosed
US-20060122100-A1 Melanin extinguisher OGA RESEARCH, INCORPORATED (JP) 2006-06-08 US disclosed
EP-1547590-A1 MELANIN EXTINGUISHER Oga Research, Incorporated (JP) 2005-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060122100-A1 Melanin extinguisher TYR, MC1R, MITF SLC6A5 2176/4885FOLH1 3374/4885NOD1 4616/4885
US-20090093541-A1 MELANIN ELIMINATOR PREPARATION TYR, MC1R, MCHR1 SLC6A5 1510/4885FOLH1 1909/4885NOD1 4460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.