Isocitrate

Isocitrate

SCHEMBL2580642

N.N.N.O=C(O)CC(C(=O)O)C(O)C(=O)O

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.74
SMN1; SMN2 Q16637 1/20 0.48
SLC22A6 Q4U2R8 1/20 0.46
TSHR P16473 2/20 0.45
GABRR1 P24046 2/20 0.39
LMNA P02545 1/20 0.39
CYP2C9 P11712 1/20 0.36
PDE4A P27815 1/20 0.36
FOLH1 Q04609 1/20 0.36
MAPT P10636 1/20 0.34
TET2 Q6N021 3/20 0.33
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
TET3 O43151 1/20 0.33
CPT2 P23786 1/20 0.33
ACLY P53396 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isocitrate SCHEMBL2580646 1.00 TDP1 (0.74) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitric Acid SCHEMBL27894954 0.97 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitric Acid SCHEMBL30700829 0.97 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitric Acid SCHEMBL2794437 0.97 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitric Acid SCHEMBL6249818 0.97 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitrate SCHEMBL1289944 0.97 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitrate SCHEMBL8373 0.97 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitric Acid SCHEMBL12927570 0.97 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitric Acid SCHEMBL29645996 0.97 TDP1 (0.68) TDP1SMN1; SMN2SLC22A6TSHRGABRR1
Isocitrate SCHEMBL23648394 0.95 TDP1 (0.65) TDP1SMN1; SMN2SLC22A6TSHRGABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5990032-A COMBINING ZSM-5 ZEOLITE, PROMOTER SELECTED FROM A LIST OF METAL COMPOUNDS, AND A COMPLEXING LIGAND CAPABLE OF CHELATING THE METAL COMPOUND CONSISTING OF A CARBOXYLIC ACID OR SALT AND AN AMINO CONTAINING HYDROXY GROUP(S); CALCINING PHILLIPS PETROLEUM COMPANY (US) 1999-11-23 US claimed
US-5478802-A Injecting a solution of brine, a water-soluble polymer, a complexing ligand and a crosslinker PHILLIPS PETROLEUM COMPANY (US) 1995-12-26 US claimed
EP-0668432-A2 Process for treating oil-bearing formation PHILLIPS PETROLEUM COMPANY (US) 1995-08-23 EP claimed
US-5423380-A Adding crosslinking agent intermittently to stream of aqueous solution of gellable polymer injected into subterranean formation PHILLIPS PETROLEUM COMPANY (US) 1995-06-13 US claimed
EP-0604988-A2 Gelling compositions useful for oil field applications PHILLIPS PETROLEUM COMPANY (US) 1994-07-06 EP claimed
EP-2027956-B1 PROCESS FOR PRODUCTION OF COLLOIDAL GOLD TANAKA PRECIOUS METAL IND (JP) 2017-07-05 EP disclosed
CN-106449109-A Electrolytic capacitor long-service-life working electrolyte 安徽飞达电气科技有限公司 2017-02-22 CN disclosed
CN-106449108-A Electrolytic capacitor high-temperature-resistance working electrolyte 安徽飞达电气科技有限公司 2017-02-22 CN disclosed
CN-106373783-A High-performance working electrolyte solution for capacitor 安徽飞达电气科技有限公司 2017-02-01 CN disclosed
US-8048193-B2 Method for producing gold colloid and gold colloid TANAKA KIKINZOKU KOGYO K.K. (JP) 2011-11-01 US disclosed
US-20100159471-A1 PROCESS FOR PRODUCTION OF COLLOIDAL GOLD AND COLLOIDAL GOLD TANAKA KIKINZOKU KOGYO K.K. (JP) 2010-06-24 US disclosed
EP-2027956-A1 PROCESS FOR PRODUCTION OF COLLOIDAL GOLD AND COLLOIDAL GOLD Tanaka Kikinzoku Kogyo K.K. (JP) 2009-02-25 EP disclosed
EP-1064339-A4 COMPOSITIONS AND PROCESSES FOR OIL FIELD APPLICATIONS CONOCOPHILLIPS CO (US) 2007-09-26 EP disclosed
EP-1064339-A1 COMPOSITIONS AND PROCESSES FOR OIL FIELD APPLICATIONS Phillips Petroleum Company (US) 2001-01-03 EP disclosed
WO-1999047624-A1 COMPOSITIONS AND PROCESSES FOR OIL FIELD APPLICATIONS PHILLIPS PETROLEUM COMPANY (US) 1999-09-23 WO disclosed
US-5849674-A Compositions and processes for oil field applications PHILLIPS PETROLEUM COMPANY (US) 1998-12-15 US disclosed