⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242269 | 0.76 | MGLL (0.30) | — | |
| SCHEMBL1509172 | 0.73 | — | — | |
| SCHEMBL12468909 | 0.71 | MGLL (0.31) | — | |
| SCHEMBL27951571 | 0.71 | DGAT1 (0.30) | — | |
| SCHEMBL30645405 | 0.70 | — | — | |
| SCHEMBL30287984 | 0.70 | — | — | |
| SCHEMBL13447721 | 0.70 | MGLL (0.33) | — | |
| SCHEMBL24040328 | 0.70 | DGAT1 (0.32) | — | |
| SCHEMBL417617 | 0.70 | — | — | |
| SCHEMBL12700516 | 0.69 | MGLL (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699491-B1 | BRANCHED POLYETHYLENE GLYCOL FOR LINKING POLYMER RESIDUES TO ANTIBODIES | UCB PHARMA SA (BE) | 2011-11-16 | — | — | EP | disclosed |
| US-7736635-B2 | Branched molecular scaffolds for linking polymer residues to biologically active moieties | UCB PHARMA S.A. (BE) | 2010-06-15 | — | — | US | disclosed |
| US-20070128150-A1 | Branched molecular scaffolds for linking polymer residues to biologically active moieties | UCB BIOPHARMA SPRL (BE) | 2007-06-07 | — | — | US | disclosed |
| EP-1699491-A2 | BRANCHED POLYETHYLENE GLYCOL FOR LINKING POLYMER RESIDUES TO ANTIBODIES | Celltech R&D Limited (GB) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005061005-A2 | BRANCHED POLYETHYLENE GLYCOL FOR LINKING POLYMER RESIDUES TO ANTIBODIES | CELLTECH R & D LIMITED (GB) | 2005-07-07 | — | — | WO | disclosed |