Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET3 | O43151 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | FBXL19 | Q6PCT2 | 4/20 | 0.38 |
| ▸ | CXXC5 | Q7LFL8 | 4/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.38 |
| ▸ | CXXC4 | Q9H2H0 | 4/20 | 0.38 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.38 |
| ▸ | TET1 | Q8NFU7 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 8/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 4/20 | 0.34 |
| ▸ | TXK | P42681 | 3/20 | 0.34 |
| ▸ | ITK | Q08881 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | TEC | P42680 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31580332 | 0.83 | CYP11B1 (0.40) | CYP11B1CYP11B2PIK3CD | |
| SCHEMBL29626701 | 0.81 | CYP11B1 (0.39) | CYP11B1CYP11B2PIK3CD | |
| SCHEMBL16600198 | 0.78 | CYP11B1 (0.41) | KMT2ACYP11B1CYP11B2PIK3CD | |
| SCHEMBL16102404 | 0.77 | TET3 (0.41) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL20849781 | 0.76 | TET3 (0.45) | TET3KMT2AFBXL19CXXC5KDM2B | |
| SCHEMBL16600640 | 0.76 | GRM5 (0.36) | CYP11B1CYP11B2 | |
| SCHEMBL289351 | 0.76 | OPRM1 (0.42) | KMT2ACYP11B1CYP11B2PIK3CD | |
| SCHEMBL30620935 | 0.74 | POLB (0.38) | KMT2ACYP11B1CYP11B2PIK3CD | |
| SCHEMBL19032234 | 0.74 | CYP11B2 (0.45) | CYP11B2 | |
| SCHEMBL29889297 | 0.74 | CYP11B1 (0.41) | KMT2ACYP11B1CYP11B2PIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129332-A1 | COVALENT MOLECULAR GLUE STABILIZERS AND PLATFORM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-07-06 | — | — | WO | disclosed |