Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | FPR3 | P25089 | 2/20 | 0.40 |
| ▸ | FPR2 | P25090 | 2/20 | 0.40 |
| ▸ | LATS1 | O95835 | 1/20 | 0.40 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15341063 | 0.93 | STK17B (0.51) | STK17BSTK17AFPR3FPR2P2RY2 | |
| SCHEMBL25003064 | 0.82 | STK17B (0.49) | BCHESTK17BSTK17AMALT1FPR3 | |
| SCHEMBL15340890 | 0.82 | FPR3 (0.45) | STK17BSTK17AFPR3FPR2TDP1 | |
| SCHEMBL640612 | 0.81 | CA1 (0.45) | FPR3FPR2CA1CA2CCNB2 | |
| SCHEMBL15344189 | 0.81 | P2RY2 (0.42) | STK17BSTK17AFPR3FPR2P2RY2 | |
| SCHEMBL15344173 | 0.81 | P2RY2 (0.42) | STK17BSTK17AFPR3FPR2P2RY2 | |
| SCHEMBL2411774 | 0.81 | ALDH1A1 (0.43) | STK17BSTK17AFPR3FPR2TDP1 | |
| SCHEMBL4299723 | 0.81 | BCHE (0.43) | BCHESTK17BSTK17AMALT1FPR3 | |
| SCHEMBL15328471 | 0.81 | P2RY2 (0.47) | P2RY2ALDH1A1 | |
| SCHEMBL15340923 | 0.81 | P2RY2 (0.56) | P2RY2TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675847-B1 | SPIROCYCLE COMPOUNDS AND METHODS OF MAKING AND USING SAME | H LUNDBECK AS (DK) | 2023-07-12 | — | — | EP | disclosed |