Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4A3 | P38919 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3633240 | 0.84 | EIF4A3 (0.54) | EIF4A3KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL25810893 | 0.83 | ALOX15 (0.60) | KDM4EHPGDHSD17B10MAPTALDH1A1 | |
| SCHEMBL27785515 | 0.79 | EIF4A3 (0.48) | EIF4A3KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL29865102 | 0.77 | EIF4A3 (0.55) | EIF4A3KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL3033200 | 0.77 | EIF4A3 (0.55) | EIF4A3KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28578488 | 0.76 | KDM4E (0.54) | EIF4A3KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL5261401 | 0.74 | MMP2 (0.54) | EIF4A3KDM4EHPGDHSD17B10MAPT | |
| Hydrochloric Acid SCHEMBL16395943 | 0.74 | EIF4A3 (0.49) | EIF4A3KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL30909341 | 0.74 | HSD17B10 (0.51) | EIF4A3KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL30909340 | 0.74 | HSD17B10 (0.51) | EIF4A3KDM4EHPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125376-A1 | FUSED BICYCLIC HETEROARYL AMIDE COMPOUND AS PROTEIN AGGREGATION INHIBITOR | 上海京新生物医药有限公司 | 2023-07-06 | — | — | WO | disclosed |