Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24680252 | 0.86 | GABRA1 (0.41) | GABRA1CYP1A2GABRB2GABRG2GABRB3 | |
| SCHEMBL25826783 | 0.79 | MEN1 (0.38) | CYP3A4HTR2BHTR2AMEN1ALDH1A1 | |
| SCHEMBL24680253 | 0.79 | CYP1A2 (0.39) | GABRA1CYP1A2GABRB2GABRG2GABRB3 | |
| SCHEMBL26707307 | 0.79 | MEN1 (0.36) | GABRA1CYP1A2GABRB2GABRG2GABRB3 | |
| SCHEMBL27300600 | 0.78 | GABRA1 (0.42) | GABRA1CYP1A2GABRB2GABRG2GABRB3 | |
| SCHEMBL25905423 | 0.77 | CYP1A2 (0.41) | GABRA1CYP1A2GABRB2GABRG2GABRB3 | |
| SCHEMBL26707287 | 0.76 | P2RX7 (0.38) | GABRA1CYP1A2GABRB2GABRG2GABRB3 | |
| SCHEMBL24680262 | 0.76 | CYP1A2 (0.39) | GABRA1CYP1A2GABRB2GABRG2GABRB3 | |
| SCHEMBL26502469 | 0.76 | GABRA1 (0.39) | GABRA1CYP1A2GABRB2GABRG2GABRB3 | |
| SCHEMBL26502473 | 0.76 | GABRA1 (0.39) | GABRA1CYP1A2GABRB2GABRG2GABRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |