Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 4/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.30 |
| ▸ | FEN1 | P39748 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31314110 | 0.71 | TDP1 (0.35) | — | |
| SCHEMBL31435345 | 0.70 | BACE1 (0.36) | NOTUMPNMTALOX5APFEN1 | |
| SCHEMBL31435343 | 0.70 | BACE1 (0.36) | NOTUMPNMTALOX5APFEN1 | |
| SCHEMBL24738092 | 0.68 | CA2 (0.33) | — | |
| SCHEMBL24857294 | 0.68 | NOS3 (0.41) | — | |
| SCHEMBL22062848 | 0.68 | KRAS (0.33) | NOTUMCNR2 | |
| SCHEMBL25827014 | 0.67 | NOS3 (0.38) | CNR2ALOX5APFEN1 | |
| SCHEMBL24784940 | 0.67 | KRAS (0.34) | NOTUMCNR2 | |
| SCHEMBL25223677 | 0.66 | CNR2 (0.36) | CNR2 | |
| SCHEMBL31140849 | 0.66 | CNR2 (0.36) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125989-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | 上海医药集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |