Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | ECE1 | P42892 | 3/20 | 0.36 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | FCER2 | P06734 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19302558 | 0.89 | GABRR1 (0.39) | GABRR1MMENAALAD2FOLH1ECE1 | |
| SCHEMBL24753917 | 0.89 | GABRR1 (0.39) | GABRR1MMENAALAD2FOLH1ECE1 | |
| SCHEMBL24141307 | 0.89 | GABRR1 (0.39) | GABRR1MMENAALAD2FOLH1ECE1 | |
| SCHEMBL23346342 | 0.84 | GABRR1 (0.38) | GABRR1MMENAALAD2FOLH1ECE1 | |
| SCHEMBL22241557 | 0.83 | ECE1 (0.39) | MMENOD1ECE1MMP1FCER2 | |
| SCHEMBL25011832 | 0.81 | NAALAD2 (0.40) | GABRR1MMENAALAD2FOLH1ECE1 | |
| SCHEMBL19302568 | 0.76 | ECE1 (0.35) | GABRR1MMENAALAD2FOLH1NOD1 | |
| SCHEMBL24760234 | 0.74 | FOLH1 (0.43) | GABRR1MMENAALAD2FOLH1 | |
| SCHEMBL14355656 | 0.74 | FOLH1 (0.43) | GABRR1MMENAALAD2FOLH1 | |
| SCHEMBL10020473 | 0.74 | CA2 (0.53) | MMENAALAD2FOLH1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212181-A2 | METHYLENE CARBAMATE LINKERS FOR USE WITH TARGETED-DRUG CONJUGATES | Seagen Inc. (US) | 2023-07-19 | — | — | EP | disclosed |