SCHEMBL25811843

SCHEMBL25811843

c1cc(-c2ccc3cc[nH]c3c2)cc(-c2nc(-c3ccc4ccccc4c3)nc(-c3ccc4ccccc4c3)n2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.50
ADORA2A P29274 2/20 0.48
ADORA1 P30542 2/20 0.48
HSD17B1 P14061 1/20 0.44
HSD17B2 P37059 1/20 0.44
GHSR Q92847 3/20 0.43
TRPA1 O75762 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
ITGB2 P05107 1/20 0.43
ICAM1 P05362 1/20 0.43
ITGAL P20701 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
AHR P35869 1/20 0.43
ADK P55263 1/20 0.43
BACE1 P56817 1/20 0.42
CYP11B1 P15538 2/20 0.41
CYP11B2 P19099 2/20 0.41
CYP17A1 P05093 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7084471 0.87 NPC1 (0.58) NPC1ADORA2AADORA1HSD17B1HSD17B2
SCHEMBL21667606 0.83 HSD17B1 (0.59) HSD17B1HSD17B2CA1CA2CYP11B1
SCHEMBL24353250 0.83 HSD17B1 (0.59) HSD17B1HSD17B2CA1CA2CYP11B1
SCHEMBL21667461 0.83 HSD17B1 (0.59) HSD17B1HSD17B2CA1CA2CYP11B1
SCHEMBL22186308 0.83 HSD17B1 (0.59) HSD17B1HSD17B2CA1CA2CYP11B1
SCHEMBL7088159 0.82 NPC1 (0.67) NPC1ADORA2AADORA1GHSRTRPA1
SCHEMBL24377037 0.80 HSD17B1 (0.55) ADORA2AADORA1HSD17B1HSD17B2CA1
SCHEMBL24377159 0.80 HSD17B1 (0.55) ADORA2AADORA1HSD17B1HSD17B2CA1
SCHEMBL24353249 0.80 MEN1 (0.56) ADORA2AADORA1HSD17B1HSD17B2CYP11B1
SCHEMBL24353200 0.80 HSD17B1 (0.55) ADORA2AADORA1HSD17B1HSD17B2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4273148-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC ELEMENT, COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE Samsung SDI Co., Ltd. (KR) 2023-11-08 EP disclosed
EP-4212517-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC ELEMENT, COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE Samsung SDI Co., Ltd. (KR) 2023-07-19 EP disclosed