Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | GHSR | Q92847 | 3/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 4/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.48 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.48 |
| ▸ | ITGAL | P20701 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.47 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL443799 | 0.96 | NPC1 (0.71) | NPC1ADORA2AADORA1GHSRFGFR1 | |
| SCHEMBL30253604 | 0.96 | NPC1 (0.71) | NPC1ADORA2AADORA1GHSRFGFR1 | |
| SCHEMBL7084471 | 0.82 | NPC1 (0.58) | NPC1ADORA2AADORA1GHSRAHR | |
| SCHEMBL24601496 | 0.82 | NPC1 (0.50) | NPC1ADORA2AADORA1GHSRAHR | |
| SCHEMBL7091322 | 0.82 | NPC1 (0.54) | NPC1ADORA2AADORA1GHSRAHR | |
| SCHEMBL25811843 | 0.82 | NPC1 (0.50) | NPC1ADORA2AADORA1GHSRAHR | |
| SCHEMBL5464492 | 0.81 | NPC1 (0.49) | NPC1ADORA2AADORA1GHSRAHR | |
| SCHEMBL5664020 | 0.81 | AHR (0.63) | NPC1ADORA2AADORA1AHRCMA1 | |
| SCHEMBL7087919 | 0.81 | AHR (0.63) | NPC1ADORA2AADORA1GHSRAHR | |
| SCHEMBL981855 | 0.81 | ADORA2A (0.52) | NPC1ADORA2AADORA1AHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | 4SC AG (DE) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203959-A1 | Novel modulators of potassium channels | HCN3, KCNN3, KCNN1 | NPC1 487/4885ADORA2A 883/4885ADORA1 347/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.