Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24171866 | 0.90 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1HCRTR1POLB | |
| SCHEMBL24171418 | 0.90 | MAPT (0.43) | ALDH1A1MAPTL3MBTL1HCRTR1POLB | |
| SCHEMBL14133854 | 0.89 | MAPT (0.51) | ALDH1A1MAPTL3MBTL1HCRTR1POLB | |
| SCHEMBL16283926 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1HCRTR1POLB | |
| SCHEMBL13815227 | 0.87 | MAPT (0.46) | ALDH1A1MAPTL3MBTL1HCRTR1POLB | |
| SCHEMBL29178545 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MAPTL3MBTL1HCRTR1POLB | |
| SCHEMBL14798075 | 0.83 | GPR3 (0.48) | ALDH1A1MAPTL3MBTL1HCRTR1POLB | |
| SCHEMBL31208546 | 0.83 | GPR3 (0.48) | ALDH1A1MAPTL3MBTL1HCRTR1POLB | |
| SCHEMBL24557536 | 0.79 | ESR2 (0.41) | ALDH1A1MAPTL3MBTL1HCRTR1POLB | |
| SCHEMBL17689841 | 0.78 | GPR3 (0.57) | ALDH1A1MAPTHCRTR1TNKSTNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3880682-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2023-06-14 | — | — | EP | disclosed |