Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 5/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.40 |
| ▸ | WNT1 | P04628 | 10/20 | 0.40 |
| ▸ | GSK3B | P49841 | 9/20 | 0.40 |
| ▸ | TTK | P33981 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25813252 | 0.90 | DYRK1A (0.42) | KIFC1DYRK1AWNT1GSK3BTTK | |
| SCHEMBL25254036 | 0.84 | DYRK1A (0.37) | KIFC1DYRK1AWNT1GSK3BTTK | |
| SCHEMBL25294342 | 0.84 | DYRK1A (0.37) | KIFC1DYRK1AWNT1GSK3BTTK | |
| SCHEMBL25813063 | 0.83 | KIFC1 (0.55) | KIFC1 | |
| SCHEMBL25813384 | 0.80 | KIFC1 (0.64) | KIFC1 | |
| SCHEMBL30497105 | 0.78 | DYRK1A (0.41) | DYRK1AWNT1GSK3BTTK | |
| SCHEMBL25813253 | 0.78 | DYRK1A (0.41) | DYRK1AWNT1GSK3BTTK | |
| SCHEMBL25301269 | 0.77 | DYRK1A (0.40) | DYRK1AWNT1GSK3BTTK | |
| SCHEMBL25301266 | 0.77 | DYRK1A (0.40) | DYRK1AWNT1GSK3BTTK | |
| SCHEMBL25261091 | 0.76 | DYRK1A (0.47) | DYRK1AWNT1GSK3BTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131690-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |