Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KIFC1 | Q9BW19 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.47 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.47 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30497107 | 0.84 | L3MBTL1 (0.70) | PLK1L3MBTL1KIFC1MAPTTP53 | |
| SCHEMBL225165 | 0.84 | L3MBTL1 (0.70) | PLK1L3MBTL1KIFC1MAPTTP53 | |
| SCHEMBL1300650 | 0.83 | L3MBTL1 (0.64) | PLK1L3MBTL1KIFC1MAPTTP53 | |
| SCHEMBL1020649 | 0.82 | L3MBTL1 (0.68) | PLK1L3MBTL1KIFC1MAPTTP53 | |
| SCHEMBL326777 | 0.82 | L3MBTL1 (0.68) | PLK1L3MBTL1KIFC1MAPTTP53 | |
| SCHEMBL30454185 | 0.82 | L3MBTL1 (0.68) | PLK1L3MBTL1KIFC1MAPTTP53 | |
| SCHEMBL11962152 | 0.82 | PLK1 (1.00) | PLK1L3MBTL1MAPTTP53HDAC8 | |
| SCHEMBL25254573 | 0.81 | KIFC1 (0.60) | PLK1L3MBTL1KIFC1MAPTTP53 | |
| SCHEMBL30497131 | 0.81 | KIFC1 (0.60) | PLK1L3MBTL1KIFC1MAPTTP53 | |
| SCHEMBL7554084 | 0.81 | PLK1 (0.97) | PLK1L3MBTL1MAPTTP53HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131690-A1 | SUBSTITUTED HETEROCYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | WO | disclosed |