SCHEMBL25814633

SCHEMBL25814633

C=CCOC1COc2ccc(C(C)(C)C)cc2OCCCOc2ccc(C(C)(C)C)cc2OC1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.36
TRPV1 Q8NER1 11/20 0.36
HRH3 Q9Y5N1 1/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 2/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
MTOR P42345 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPC1 O15118 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25815406 0.84 CYP19A1 (0.38) CYP19A1TRPV1MAPTALDH1A1LMNA
SCHEMBL22134638 0.80 ALDH1A1 (0.41) CYP19A1TRPV1MAPTALDH1A1LMNA
SCHEMBL25815359 0.78 ALDH1A1 (0.41) CYP19A1TRPV1MAPTALDH1A1LMNA
SCHEMBL22134735 0.77 TRPV1 (0.46) TRPV1MAPTRAB9AMEN1TSHR
SCHEMBL9883695 0.77 TRPV1 (0.46) TRPV1MAPTRAB9AMEN1TSHR
SCHEMBL25815131 0.76 CYP19A1 (0.41) CYP19A1TRPV1MAPTALDH1A1RAB9A
SCHEMBL22134641 0.75 TRPV1 (0.43) CYP19A1TRPV1MAPTALDH1A1LMNA
SCHEMBL22134634 0.75 CYP19A1 (0.39) CYP19A1TRPV1MAPTRAB9AMEN1
SCHEMBL22134742 0.75 TRPV1 (0.39) CYP19A1TRPV1MAPTALDH1A1RAB9A
SCHEMBL12744647 0.74 TRPV1 (0.46) TRPV1MAPTRAB9AMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230219919-A1 LITHIUM EXTRACTION WITH CROWN ETHERS ORCA HOLDINGS, LLC 2023-07-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230219919-A1 LITHIUM EXTRACTION WITH CROWN ETHERS LCLAT1, LCT, IGF2R CYP19A1 4811/4885TRPV1 434/4885HRH3 1515/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.