Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 9/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16852527 | 1.00 | PDK2 (0.41) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL16852534 | 0.99 | PDK2 (0.40) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL17465482 | 0.99 | PDK2 (0.42) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL17805085 | 0.99 | PDK2 (0.42) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL19444946 | 0.97 | PDK2 (0.41) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL16996139 | 0.97 | PDK2 (0.43) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL17854536 | 0.96 | MEN1 (0.39) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL16922950 | 0.96 | PDK2 (0.40) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL18912545 | 0.96 | PDK2 (0.42) | PDK2ESR1ESR2MEN1KMT2A | |
| SCHEMBL16996428 | 0.96 | PDK2 (0.42) | PDK2ESR1ESR2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230225196-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230225196-A1 | MATERIALS FOR ELECTRONIC DEVICES | SELE, EPHA6, EPX | PDK2 1021/4885ESR1 31/4885ESR2 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.