Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815487 | 0.89 | SLC6A2 (0.45) | SLC6A2SLC6A3SLC6A4MAPTADRA1D | |
| SCHEMBL20365781 | 0.85 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4ADRA1DADRA1A | |
| SCHEMBL20363922 | 0.84 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4MAPTADRA1A | |
| SCHEMBL29493267 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1HTR6KDM4E | |
| SCHEMBL2431131 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1HTR6KDM4E | |
| SCHEMBL4024455 | 0.74 | ALDH1A1 (0.51) | MAPTALDH1A1 | |
| SCHEMBL4023577 | 0.72 | ALDH1A1 (0.50) | MAPTALDH1A1 | |
| SCHEMBL4029065 | 0.72 | ALDH1A1 (0.50) | MAPTALDH1A1 | |
| SCHEMBL4027973 | 0.72 | ALDH1A1 (0.50) | MAPTALDH1A1 | |
| SCHEMBL23710929 | 0.72 | PARP1 (0.44) | ADRA1DADRA1AADRA1BALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129506-A1 | POTENT AND SELECTIVE SMARCA2 DEGRADING CHIMERIC MOLECULES AS CANCER THERAPEUTICS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-06 | — | — | WO | disclosed |