Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25815173 | 0.89 | SLC6A2 (0.44) | SLC6A2SLC6A3SLC6A4MAPTADRA1D | |
| SCHEMBL20365781 | 0.86 | SLC6A2 (0.53) | SLC6A2SLC6A3SLC6A4ADRA1DADRA1A | |
| SCHEMBL20363922 | 0.85 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4MAPTKCNH2 | |
| SCHEMBL23710929 | 0.83 | PARP1 (0.44) | PARP1KCNH2ADRA1DADRA1AADRA1B | |
| SCHEMBL25815151 | 0.80 | KDM4E (0.44) | MAPTPARP1KCNH2ADRA1DADRA1A | |
| SCHEMBL18052715 | 0.80 | ALDH1A1 (0.48) | MAPTPARP1KCNH2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10268271 | 0.78 | MAPT (0.41) | MAPTPARP1KCNH2KDM4EALDH1A1 | |
| SCHEMBL8427926 | 0.78 | ALDH1A1 (0.49) | MAPTPARP1KCNH2KDM4EALDH1A1 | |
| SCHEMBL8373055 | 0.75 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10264296 | 0.74 | PARP1 (0.42) | MAPTPARP1KCNH2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129506-A1 | POTENT AND SELECTIVE SMARCA2 DEGRADING CHIMERIC MOLECULES AS CANCER THERAPEUTICS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-06 | — | — | WO | disclosed |