SCHEMBL2581532

SCHEMBL2581532

CCOC(=O)CSC(=O)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.48
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
TDP1 Q9NUW8 1/20 0.44
TRPA1 O75762 1/20 0.44
CYP2D6 P10635 1/20 0.41
HSD17B10 Q99714 3/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 3/20 0.40
HPGD P15428 2/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MEN1 O00255 1/20 0.40
RAB9A P51151 1/20 0.40
CYP1A2 P05177 1/20 0.39
MAPT P10636 1/20 0.39
POLB P06746 1/20 0.38
ALOX15 P16050 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18113273 0.79 GAA (0.50) ALDH1A1MGAMGAASIMGAM2
SCHEMBL11092006 0.79 MGAM (0.50) ALDH1A1MGAMGAASIMGAM2
SCHEMBL18113081 0.79 GAA (0.50) ALDH1A1MGAMGAASIMGAM2
SCHEMBL20216267 0.77 GAA (0.48) ALDH1A1MGAMGAASIMGAM2
SCHEMBL20204106 0.77 ALDH1A1 (0.50) ALDH1A1MGAMGAASIMGAM2
SCHEMBL6029494 0.76
SCHEMBL9596735 0.76 ALDH1A1 (0.53) ALDH1A1MGAMGAASIMGAM2
SCHEMBL165143 0.76 ALDH1A1 (0.48) ALDH1A1MGAMGAASIMGAM2
SCHEMBL14865008 0.76 ALDH1A1 (0.70) ALDH1A1MGAMGAASIMGAM2
SCHEMBL13712744 0.76 GAA (0.52) ALDH1A1MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8598078-B2 Condensed anthran I lami de derivatives as insecticides SYNGENTA CROP PROTECTION, LLC (US) 2013-12-03 US disclosed
EP-2178859-B1 CONDENSED ANTHRANILAMIDE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-12-21 EP disclosed
EP-2178859-B1 CONDENSED ANTHRANILAMIDE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG (CH) 2011-12-21 EP disclosed
US-20110271406-A1 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTICIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-11-03 US disclosed
US-20110271406-A1 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTICIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-11-03 US disclosed
US-20110271406-A1 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTICIDES SYNGENTA CROP PROTECTION, INC. (US) 2011-11-03 US disclosed
EP-2178859-A2 CONDENSED ANTHRANILAMIDE DERIVATIVES AS INSECTISIDES Syngenta Participations AG (CH) 2010-04-28 EP disclosed
WO-2009024341-A2 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG, (CH) 2009-02-26 WO disclosed
WO-2009024341-A2 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTISIDES SYNGENTA PARTICIPATIONS AG, (CH) 2009-02-26 WO disclosed
EP-0577193-B1 Photographic element comprising a combination of a development inhibiting releasing coupler and a bleach accelerator releasing compound EASTMAN KODAK CO (US) 1999-09-08 EP disclosed
US-5358828-A Coupler capable of forming wash-out dye EASTMAN KODAK COMPANY (US) 1994-10-25 US disclosed
US-5318879-A Photographic element comprising a bleach accelerator releasing compound EASTMAN KODAK COMPANY (US) 1994-06-07 US disclosed
US-5300406-A Coupler which forms dye that washes out during processing EASTMAN KODAK COMPANY (US) 1994-04-05 US disclosed
US-5286859-A Bleach accelerating releasing coupler; forming chloroformate with phosgene, reacting with a thiol EASTMAN KODAK COMPANY (US) 1994-02-15 US disclosed
EP-0577190-A2 Photographic element comprising a bleach accelerator releasing compound containing an acid solubilizing group EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
EP-0577191-A2 Photographic element and process comprising a bleach accelerator releasing compound and methods of making such compound EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
EP-0577193-A1 Photographic element comprising a combination of a development inhibiting releasing coupler and a bleach accelerator releasing compound EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
EP-0577192-A1 Photographic element comprising a dir coupler and a barc coupler containing an acid solubilizing group EASTMAN KODAK COMPANY (US) 1994-01-05 EP disclosed
US-4051250-A OXAZOLE, THIAZOLE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1977-09-27 US disclosed
US-3933840-A ANTIPHLOGISTIC MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110271406-A1 CONDENSED ANTHRAN I LAMI DE DERIVATIVES AS INSECTICIDES ECI1, FURIN, DDT ALDH1A1 72/4885MGAM 3215/4885GAA 1088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.