Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ITK | Q08881 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25457307 | 0.90 | CA12 (0.46) | EGFRITKSCN9AAAK1FDPS | |
| SCHEMBL21549514 | 0.89 | EGFR (0.44) | EGFRITKADRB2HTR1ASCN9A | |
| SCHEMBL30444087 | 0.89 | EGFR (0.44) | EGFRITKADRB2HTR1ASCN9A | |
| SCHEMBL29948350 | 0.88 | CA12 (0.48) | EGFRITKSCN9AAAK1CA12 | |
| SCHEMBL20102825 | 0.88 | CA12 (0.48) | EGFRITKSCN9AAAK1CA12 | |
| SCHEMBL29948353 | 0.88 | CA12 (0.48) | EGFRITKSCN9AAAK1CA12 | |
| SCHEMBL24838619 | 0.88 | ADRB2 (0.45) | EGFRITKADRB2HTR1ABCHE | |
| SCHEMBL18569779 | 0.88 | ADRB2 (0.45) | EGFRITKADRB2HTR1ABCHE | |
| SCHEMBL20102815 | 0.88 | CA12 (0.48) | EGFRITKSCN9AAAK1CA12 | |
| SCHEMBL18544320 | 0.87 | FDPS (0.59) | FDPSALDH1A1HPGDCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129506-A1 | POTENT AND SELECTIVE SMARCA2 DEGRADING CHIMERIC MOLECULES AS CANCER THERAPEUTICS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-06 | — | — | WO | disclosed |