Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.41 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1450228 | 0.83 | PARP10 (0.39) | CYP3A4CYP2C19ALDH1A1CA1CA9 | |
| SCHEMBL2581571 | 0.79 | NAPRT (0.58) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10910929 | 0.77 | NAPRT (0.50) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL7439433 | 0.77 | NAPRT (0.56) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28774639 | 0.77 | NAPRT (0.50) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30475739 | 0.77 | HCAR2 (0.55) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL524788 | 0.76 | MAPT (0.56) | NAPRTCYP3A4CYP2C19KDM4EALDH1A1 | |
| SCHEMBL11583767 | 0.76 | NAPRT (0.54) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| Formaldehyde SCHEMBL29045130 | 0.76 | CYP17A1 (0.55) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8582840 | 0.75 | NAPRT (0.59) | NAPRTCYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4188551-B1 | ARYL SUBSTITUTED PYRROLO-PYRIDINONES AND THERAPEUTIC USES THEREOF | BAYER AG (DE) | 2024-12-18 | — | — | EP | claimed |
| EP-4188551-A1 | ARYL SUBSTITUTED PYRROLO-PYRIDINONES AND THERAPEUTIC USES THEREOF | Bayer Aktiengesellschaft (DE) | 2023-06-07 | — | — | EP | claimed |
| EP-3921317-A1 | 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS | Bayer Aktiengesellschaft (DE) | 2021-12-15 | — | — | EP | claimed |
| WO-2020161257-A1 | 3-AMINO-2-[2-(ACYLAMINO)PYRIDIN-4-YL]-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE AS CSNK1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-08-13 | — | — | WO | claimed |
| JP-4555547-B2 | — | — | 2010-10-06 | — | — | JP | claimed |
| JP-2004505977-A | — | — | 2004-02-26 | — | — | JP | claimed |
| EP-1320531-A2 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2003-06-25 | — | — | EP | claimed |
| WO-2002012242-A2 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2002-02-14 | — | — | WO | claimed |
| CN-110183422-B | Nuclear transport modulators and uses thereof | 卡尔约药物治疗公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-110386919-B | Nuclear transport modulators and uses thereof | 卡尔约药物治疗公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2022089629-A1 | 1,2,4-TRIAZOLE DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏柯菲平医药股份有限公司 | 2022-05-05 | — | — | WO | disclosed |
| CN-110386919-A | Nuclear translocation regulator and application thereof | 卡尔约药物治疗公司 | 2019-10-29 | — | — | CN | disclosed |
| CN-110183422-A | Nuclear translocation regulator and application thereof | 卡尔约药物治疗公司 | 2019-08-30 | — | — | CN | disclosed |
| CN-105339358-B | Nuclear transport modulators and uses thereof | 卡尔约药物治疗公司 | 2019-06-04 | — | — | CN | disclosed |
| US-20100025642-A1 | ULTRAVIOLET ABSORBENT COMPOSITION | FUJIFILM CORPORATION (JP) | 2010-02-04 | — | — | US | disclosed |
| CN-101605795-A | Tricyclic compounds and pharmaceutical uses thereof | TAKEDA PHARMACEUTICAL (JP) | 2009-12-16 | — | — | CN | disclosed |
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | FUJIFILM CORPORATION (JP) | 2009-09-24 | — | — | US | disclosed |
| US-6743794-B2 | MULTIDRUG RESISTANCE PROTEIN; CANCER; 3-(9-CHLORO-3-METHYL-4-OXO-5H-ISOXAZOLO(4,3-C)QUINOLIN-5-YL)) CYCLOHEXYL)-2-PIPERIDYLACETAMIDE | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |
| EP-1320531-A2 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | Pharmacia Italia S.p.A. (IT) | 2003-06-25 | — | — | EP | disclosed |
| WO-2002012242-A2 | BICYCLO-PYRAZOLES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PHARMACIA ITALIA S.P.A. (IT) | 2002-02-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090240067-A1 | METHOD OF PRODUCING A BISBENZODITHIOL COMPOUND | SQOR, NQO1, PBRM1 | NAPRT 1466/4885CYP1A2 219/4885CYP3A4 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.