Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.30 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25565669 | 0.91 | NCF1 (0.36) | ACHEOPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL21946386 | 0.85 | NCF1 (0.42) | ACHECHRM5ADRA2CGNAI3GNAO1 | |
| SCHEMBL680627 | 0.84 | ACHE (0.47) | ACHEOPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL26748263 | 0.83 | OPRL1 (0.37) | ACHEOPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL26445224 | 0.83 | ACHE (0.36) | ACHEOPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL21946384 | 0.83 | ACHE (0.36) | ACHEOPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL27425161 | 0.82 | ACHE (0.45) | ACHEOPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL25075153 | 0.80 | ACHE (0.38) | ACHEOPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL24926124 | 0.80 | ACHE (0.34) | ACHEOPRL1OPRM1OPRD1OPRK1 | |
| SCHEMBL26494097 | 0.80 | ACHE (0.34) | ACHEOPRL1OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |