Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 4/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | STAMBP | O95630 | 1/20 | 0.36 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6409445 | 0.86 | USP7 (0.36) | HPGDALDH1A1SMN1; SMN2NAMPTUSP7 | |
| SCHEMBL2400885 | 0.86 | ABL1 (0.46) | HPGDALDH1A1SMN1; SMN2NAMPTNPC1 | |
| SCHEMBL2401319 | 0.84 | SMN1; SMN2 (0.41) | HPGDALDH1A1SMN1; SMN2NAMPTUSP7 | |
| SCHEMBL2402433 | 0.83 | CHRM4 (0.41) | NAMPTEPHX1EPHX2CHRM4 | |
| SCHEMBL2403261 | 0.82 | HTR1A (0.45) | ALDH1A1KDM4E | |
| SCHEMBL2401978 | 0.80 | RAB9A (0.45) | HPGDALDH1A1NPC1RAB9AEPHX2 | |
| SCHEMBL6409614 | 0.80 | EPHX2 (0.39) | HPGDALDH1A1SMN1; SMN2USP7NPC1 | |
| SCHEMBL2575305 | 0.78 | SMN1; SMN2 (0.45) | HPGDALDH1A1SMN1; SMN2TSHREPHX2 | |
| SCHEMBL2402651 | 0.78 | HPGD (0.43) | HPGDALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2401308 | 0.77 | HPGD (0.41) | HPGDALDH1A1SMN1; SMN2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048890-B2 | Analgesics; neuropathic pain; headaches; muscle relaxants; incontence; tinnitus; diarrhea; antiarrhythmia agents; antiischemic agents; antiinflammatory agents; antiulcer agents; antidepressants; antiepileptic agents | GRUENENTHAL GMBH (DE) | 2011-11-01 | — | — | US | claimed |