Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15150972 | 0.96 | TAAR1 (0.38) | TAAR1GGPS1HIF1ACETPTP53 | |
| SCHEMBL15151000 | 0.96 | TAAR1 (0.38) | TAAR1GGPS1HIF1ACETPTP53 | |
| SCHEMBL15150988 | 0.96 | TAAR1 (0.38) | TAAR1GGPS1HIF1ACETPTP53 | |
| SCHEMBL15150987 | 0.94 | TAAR1 (0.39) | TAAR1GGPS1HIF1ATP53CYP3A4 | |
| SCHEMBL15150976 | 0.94 | TAAR1 (0.39) | TAAR1GGPS1HIF1ATP53CYP3A4 | |
| SCHEMBL15151060 | 0.94 | TAAR1 (0.39) | TAAR1GGPS1HIF1ATP53CYP3A4 | |
| SCHEMBL13881565 | 0.86 | TAAR1 (0.38) | TAAR1GGPS1HIF1ATP53CYP3A4 | |
| SCHEMBL4569003 | 0.86 | GGPS1 (0.38) | TAAR1GGPS1HIF1ACETPPPARG | |
| SCHEMBL4568992 | 0.86 | GGPS1 (0.38) | TAAR1GGPS1HIF1ACETPPPARG | |
| SCHEMBL4568989 | 0.86 | GGPS1 (0.38) | TAAR1GGPS1HIF1ACETPPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | TAAR1 1463/4885GGPS1 1289/4885HIF1A 1180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.