Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2584569 | 1.00 | FFAR2 (0.39) | FFAR2DPP4MMP13KDM1AHDAC8 | |
| SCHEMBL2588804 | 0.87 | RIPK1 (0.44) | NTRK1ALDH1A1JAK2RIPK1GPR119 | |
| SCHEMBL2583332 | 0.86 | RIPK1 (0.37) | FFAR2DPP4MMP13KDM1AHDAC8 | |
| SCHEMBL3628133 | 0.86 | STS (0.39) | FFAR2RIPK1 | |
| SCHEMBL2581199 | 0.86 | STS (0.39) | FFAR2RIPK1 | |
| SCHEMBL4087600 | 0.86 | FFAR2 (0.44) | FFAR2HCRTR2 | |
| SCHEMBL4087604 | 0.86 | FFAR2 (0.44) | FFAR2HCRTR2 | |
| SCHEMBL4501818 | 0.86 | FFAR2 (0.44) | FFAR2HCRTR2 | |
| SCHEMBL4501814 | 0.86 | FFAR2 (0.44) | FFAR2HCRTR2 | |
| SCHEMBL2584159 | 0.85 | DPP4 (0.36) | DPP4MMP13NTRK1ALDH1A1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |