Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14629574 | 0.87 | TNF (0.42) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL19451332 | 0.87 | TNF (0.42) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL22698792 | 0.85 | ALDH1A1 (0.47) | GAAALDH1A1KDM4ETP53GLA | |
| SCHEMBL22525461 | 0.85 | ANPEP (0.37) | GAAALDH1A1KDM4ETP53GLA | |
| SCHEMBL25815872 | 0.85 | GAA (0.36) | GAAALDH1A1KDM4ETP53GLA | |
| SCHEMBL20046786 | 0.85 | ALDH1A1 (0.44) | MAPTGAAGRM1ALDH1A1KDM4E | |
| SCHEMBL25814305 | 0.84 | ALDH1A1 (0.38) | GAAALDH1A1KDM4ETP53GLA | |
| SCHEMBL27404461 | 0.83 | GAA (0.34) | MAPTGAAALDH1A1KDM4ETP53 | |
| SCHEMBL22941350 | 0.83 | MEN1 (0.36) | MAPTGAAALDH1A1POLBHPGD | |
| SCHEMBL19453175 | 0.83 | GAA (0.34) | MAPTGAAALDH1A1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023129506-A1 | POTENT AND SELECTIVE SMARCA2 DEGRADING CHIMERIC MOLECULES AS CANCER THERAPEUTICS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-06 | — | — | WO | disclosed |