SCHEMBL25817005

SCHEMBL25817005

CC(=O)c1cc(C(=O)N2CCN(C(C)=O)CC2)cc(C(=O)N2CCN(C(C)=O)CC2)c1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.52
HSP90AA1 P07900 2/20 0.51
HSP90AB1 P08238 1/20 0.51
KDM4E B2RXH2 2/20 0.48
HPGD P15428 3/20 0.47
CYP1A2 P05177 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.44
ALDH1A1 P00352 2/20 0.43
KMT2A Q03164 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
POLB P06746 1/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
VNN1 O95497 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26838573 0.86 HPGD (0.65) SERPINE1HSP90AA1HSP90AB1KDM4EHPGD
SCHEMBL25817002 0.82 ALDH1A1 (0.63) KDM4EHPGDTDP1L3MBTL1ALDH1A1
SCHEMBL14882131 0.79 HPGD (0.56) SERPINE1HSP90AA1HSP90AB1KDM4EHPGD
SCHEMBL20267423 0.77 MAPK1 (0.59) HSP90AA1HSP90AB1KDM4EHPGDL3MBTL1
SCHEMBL7847889 0.76 BLM (0.66) HPGDCYP1A2ALDH1A1KMT2ASMN1; SMN2
SCHEMBL10194850 0.74 PKM (0.72) HSP90AA1HSP90AB1KDM4EHPGDALDH1A1
SCHEMBL17573009 0.74 HSP90AA1 (0.54) HSP90AA1HSP90AB1HPGDALDH1A1KMT2A
SCHEMBL14882166 0.74 ALDH1A1 (0.50) SERPINE1HSP90AA1HSP90AB1HPGDALDH1A1
SCHEMBL17559436 0.73 HSP90AA1 (0.53) HSP90AA1HSP90AB1HPGDALDH1A1KMT2A
SCHEMBL21078259 0.73 HSP90AA1 (0.53) HSP90AA1HSP90AB1HPGDALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023125806-A1 CONJUGATE FOR PREVENTING AND TREATING VIRAL INFECTIONS AND USE THEREOF 苏州爱科百发生物医药技术有限公司 2023-07-06 WO disclosed