Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.46 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13881738 | 0.90 | PARP10 (0.52) | NR1H4PARP15PARP10PARP2KAT6A | |
| SCHEMBL23115168 | 0.90 | PARP10 (0.52) | NR1H4PARP15PARP10PARP2KAT6A | |
| SCHEMBL29818710 | 0.88 | KAT6A (0.53) | NR1H4PARP15PARP10PARP2KAT6A | |
| SCHEMBL2208791 | 0.88 | KAT6A (0.53) | NR1H4PARP15PARP10PARP2KAT6A | |
| SCHEMBL2205674 | 0.88 | KAT6A (0.53) | NR1H4PARP15PARP10PARP2KAT6A | |
| SCHEMBL13749857 | 0.85 | NR1H4 (0.56) | NR1H4PARP15PARP10PARP2FABP1 | |
| SCHEMBL12952750 | 0.84 | NR1H4 (0.69) | NR1H4PARP15PARP10PARP2FABP1 | |
| SCHEMBL22779392 | 0.83 | NR1H4 (0.54) | NR1H4PARP15PARP10PARP2FABP1 | |
| SCHEMBL956474 | 0.83 | NR1H4 (0.57) | NR1H4PARP15PARP10PARP2FABP1 | |
| SCHEMBL2205755 | 0.81 | NR1H4 (0.43) | NR1H4FABP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | NR1H4 1836/4885PARP15 2575/4885PARP10 1846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.