Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2084761 | 0.82 | ADORA3 (0.42) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL2085302 | 0.80 | ADORA3 (0.41) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL13015480 | 0.77 | DAO (0.66) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL13015486 | 0.76 | ADORA3 (0.46) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL29502192 | 0.75 | DAO (0.50) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL31747293 | 0.75 | ADORA3 (0.49) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL13015488 | 0.75 | DAO (0.50) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL2085713 | 0.75 | ADORA3 (0.49) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL13954881 | 0.75 | DAO (0.64) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL2082442 | 0.75 | ADORA3 (0.49) | ADORA3ADORA2BADORA2AADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125944-A1 | COMPOUND CONTAINING HETEROCYCLIC RING | 正大天晴药业集团股份有限公司 | 2023-07-06 | — | — | WO | disclosed |