Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13015480 | 0.79 | DAO (0.66) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL10505672 | 0.79 | ADORA2B (0.54) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL13015488 | 0.78 | DAO (0.50) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL2082442 | 0.78 | ADORA3 (0.49) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL29502192 | 0.78 | DAO (0.50) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL2085713 | 0.78 | ADORA3 (0.49) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL13954881 | 0.78 | DAO (0.64) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL25939469 | 0.75 | ADORA3 (0.46) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL31731636 | 0.75 | DAO (0.44) | ADORA3ADORA2BADORA2AADORA1LMNA | |
| SCHEMBL25817348 | 0.75 | ADORA3 (0.46) | ADORA3ADORA2BADORA2AADORA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |
| EP-4667467-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | Dark Blue Therapeutics Ltd (GB) | 2025-12-24 | — | — | EP | disclosed |