Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ATF4 | P18848 | 7/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25800449 | 0.94 | ALDH1A1 (0.45) | ALDH1A1RXFP1KMT2AMEN1ATF4 | |
| SCHEMBL22628029 | 0.92 | ALDH1A1 (0.44) | ALDH1A1RXFP1KMT2AMEN1HDAC3 | |
| SCHEMBL22956187 | 0.90 | HDAC3 (0.42) | ALDH1A1RXFP1KMT2AMEN1ATF4 | |
| SCHEMBL22627652 | 0.90 | ATF4 (0.41) | ALDH1A1RXFP1KMT2AMEN1ATF4 | |
| SCHEMBL22956149 | 0.89 | ATF4 (0.39) | ALDH1A1RXFP1KMT2AMEN1ATF4 | |
| SCHEMBL22956383 | 0.89 | HDAC3 (0.40) | ALDH1A1RXFP1KMT2AMEN1ATF4 | |
| SCHEMBL22956194 | 0.88 | ATF4 (0.41) | ALDH1A1RXFP1KMT2AMEN1ATF4 | |
| SCHEMBL22627982 | 0.88 | ATF4 (0.43) | ALDH1A1RXFP1KMT2AMEN1ATF4 | |
| SCHEMBL22956242 | 0.88 | ATF4 (0.41) | ALDH1A1RXFP1KMT2AMEN1ATF4 | |
| SCHEMBL22628192 | 0.88 | ALDH1A1 (0.43) | ALDH1A1RXFP1KMT2AMEN1ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452456-B1 | BICYCLIC MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2023-07-05 | — | — | EP | disclosed |