Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 5/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.36 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569161 | 0.88 | TLR4 (0.52) | HTR2CSLC6A4TLR4TLR2PARP10 | |
| SCHEMBL18545644 | 0.77 | TLR4 (0.36) | TLR4TLR2PARP10PARP15PPARG | |
| SCHEMBL25817145 | 0.72 | TLR4 (0.46) | TLR4TLR2PARP10PARP15 | |
| SCHEMBL4569150 | 0.68 | PARP10 (0.50) | PARP10PARP15KAT6A | |
| SCHEMBL21100209 | 0.67 | BCHE (0.44) | — | |
| SCHEMBL20332387 | 0.67 | KAT6A (0.43) | HTR2CSLC6A4PARP10PARP15KAT6A | |
| SCHEMBL2206189 | 0.67 | PARP10 (0.44) | PARP10PARP15KAT6A | |
| SCHEMBL21100361 | 0.67 | TLR4 (0.46) | TLR4TLR2CACNA1B | |
| SCHEMBL21574018 | 0.66 | HTR2C (0.42) | HTR2CSLC6A4HTR2ACACNA1B | |
| SCHEMBL8911411 | 0.66 | HTR2C (0.42) | HTR2CSLC6A4HTR2ACACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ACUCELA INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230218549-A1 | ALKOXY COMPOUNDS FOR DISEASE TREATMENT | ALDH1A2, CLN6, AGER | HTR2C 2110/4885SLC6A4 1527/4885HTR2A 1163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.