SCHEMBL2581756

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13636382	0.93	FFAR1 (0.33)	RAB9ALCLAT1MAPTALDH1A1L3MBTL1
	SCHEMBL17970301	0.92	ALDH1A1 (0.34)	MAPTALDH1A1KMT2AMEN1
	SCHEMBL2493967	0.91	LCLAT1 (0.34)	HPGDTSHRNPC1RAB9ASMN1; SMN2
	SCHEMBL2466829	0.88	XBP1 (0.31)	HPGDTSHRNPC1RAB9ASMN1; SMN2
	SCHEMBL2465082	0.85	CHRM1 (0.36)	—
	SCHEMBL15996411	0.85	MAPT (0.34)	TSHRRAB9AMAPTKMT2AMEN1
	SCHEMBL14479040	0.85	PDE4D (0.38)	HPGDALDH1A1KMT2AMEN1
	SCHEMBL15472254	0.83	PDE4D (0.36)	TSHRPTGDR2MAPT
	SCHEMBL2460941	0.82	S1PR1 (0.33)	—
	SCHEMBL2458317	0.81	CHRM1 (0.39)	RAB9APTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.