Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678689 | 0.87 | DDB1 (0.56) | DDB1CRBNALDH1A1KDM4EHPGD | |
| SCHEMBL31586109 | 0.79 | DDB1 (0.50) | DDB1CRBN | |
| SCHEMBL29007105 | 0.78 | CRBN (0.59) | DDB1CRBNALDH1A1KDM4EHPGD | |
| SCHEMBL2715987 | 0.77 | GFER (0.63) | ALDH1A1KDM4ESMN1; SMN2USP2ALOX15 | |
| SCHEMBL31587053 | 0.77 | HTR1A (0.48) | DDB1CRBNALDH1A1MAPT | |
| SCHEMBL31586422 | 0.77 | HTR1A (0.48) | DDB1CRBNALDH1A1MAPT | |
| SCHEMBL30805378 | 0.76 | L3MBTL1 (0.58) | DDB1CRBNALDH1A1KDM4EHPGD | |
| SCHEMBL30678685 | 0.76 | DDB1 (0.58) | DDB1CRBNALDH1A1KDM4EHPGD | |
| SCHEMBL22144673 | 0.75 | CRBN (0.67) | DDB1CRBNALDH1A1KDM4EHPGD | |
| SCHEMBL30678700 | 0.75 | DDB1 (0.60) | DDB1CRBNALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116934-A1 | KRASG12D PROTEIN HYDROLYSIS REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州泽璟生物制药股份有限公司 | 2023-06-29 | — | — | WO | disclosed |