Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.53 |
| ▸ | CCND1 | P24385 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | AGER | Q15109 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24026926 | 1.00 | CDK4 (0.53) | CDK4CCND1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL9572684 | 0.82 | CDK4 (0.61) | CDK4CCND1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL29611307 | 0.79 | HTR2C (0.63) | CDK4CCND1HTR2AHTR2C | |
| SCHEMBL22930008 | 0.79 | CDK4 (0.57) | CDK4CCND1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL14527158 | 0.79 | HTR2C (0.63) | CDK4CCND1HTR2AHTR2C | |
| SCHEMBL29612242 | 0.79 | CDK4 (0.57) | CDK4CCND1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL12605555 | 0.79 | CDK4 (0.57) | CDK4CCND1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL19760707 | 0.79 | CDK4 (0.57) | CDK4CCND1MAPK1TSHRSMN1; SMN2 | |
| SCHEMBL2212318 | 0.79 | HTR2C (0.63) | CDK4CCND1HTR2AHTR2C | |
| SCHEMBL20912828 | 0.79 | NR3C1 (0.46) | CDK4CCND1MAPK1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | GAP43, SLC18A2, PNMT | CDK4 2526/4885CCND1 4199/4885MAPK1 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.